Search on: ELONGATION FACTOR 2 KINASE 
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Descriptor English:   Elongation Factor 2 Kinase 
Descriptor Spanish:   Quinasa del Factor 2 de Elongación 
Descriptor Portuguese:   Quinase do Fator 2 de Elongação 
Synonyms English:   Calcium-Calmodulin-Dependent Protein Kinase Type 3
Calmodulin-Dependent Protein Kinase III  
Tree Number:   D08.811.913.696.620.682.700.125.425
D12.644.360.100.425
D12.776.476.100.425
Definition English:   A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation. 
History Note English:   2008(1987) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52731 
Unique Identifier:   D054736 

Occurrence in VHL:
 

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